{"id":645,"date":"2018-04-18T16:25:08","date_gmt":"2018-04-18T14:25:08","guid":{"rendered":"http:\/\/abte.eu\/?page_id=645"},"modified":"2018-04-19T11:18:38","modified_gmt":"2018-04-19T09:18:38","slug":"dr-margot-schlusselhuber","status":"publish","type":"page","link":"https:\/\/abte.eu\/index.php\/contact\/dr-margot-schlusselhuber\/","title":{"rendered":"Dr Margot Schlusselhuber"},"content":{"rendered":"<p>Ma\u00eetre de conf\u00e9rences, section 68<\/p>\n<p>Doctorat d\u2019Universit\u00e9, Universit\u00e9 de Caen Basse Normandie (France)\/ Universit\u00e9 de Kiel (Allemagne), 2012<\/p>\n<p>&nbsp;<\/p>\n<p><strong>Int\u00e9r\u00eats de recherche<\/strong> :<strong>\u00a0<\/strong>Dans le cadre de l\u2019\u00e9tude des interactions entre microorganismes au sein de matrices alimentaires, mon activit\u00e9 porte essentiellement sur l\u2019\u00e9tude de mol\u00e9cules antimicrobiennes produites par diff\u00e9rentes bact\u00e9ries (peptides, lipopeptides, acides,&#8230;). Cette activit\u00e9 s\u2019articule autour de l\u2019identification de nouvelles mol\u00e9cules, leur caract\u00e9risation et l\u2019\u00e9tude de leurs m\u00e9canismes d\u2019action. L\u2019objectif est de valoriser certains microorganismes naturellement pr\u00e9sents dans les aliments ou leur utilisation en vue de la bioconservation de matrices alimentaires.<\/p>\n<p><strong>Composante d\u2019enseignement\u00a0:\u00a0<\/strong>Ecole d\u2019ing\u00e9nieurs ESIX Normandie, d\u00e9partement agroalimentaire<\/p>\n<p><strong>Responsabilit\u00e9s : <\/strong><\/p>\n<ul>\n<li>UE 7.3 Qualit\u00e9, S\u00e9curit\u00e9 Environnement (Esix Normandie, 2<sup>\u00e8me<\/sup> ann\u00e9e)<\/li>\n<li>Co-responsable Projets \u00e9tudiants ESIX \u2013 1<span style=\"font-size: 12px;\">ere<\/span>\u00a0ann\u00e9e<\/li>\n<li>Responsable p\u00e9dagogique Licence Professionnelle Produits Laitiers<\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n<p><strong>Liste des publications : <\/strong><\/p>\n<p>Cousin FJ, Le Guellec R,\u00a0<strong>Schlusselhuber<\/strong>\u00a0M, Dalmasso M, Laplace JM, Cretenet M. Microorganisms in Fermented Apple Beverages: Current Knowledge and Future Directions. <strong>Microorganisms<\/strong>. 2017 Jul 25;5(3)<\/p>\n<p>Berjeaud JM,\u00a0Chevalier S,\u00a0Schlusselhuber\u00a0M,\u00a0Portier E,\u00a0Loiseau C,\u00a0Aucher W,\u00a0Lesouhaitier O,\u00a0Verdon J.\u00a0<em>Legionella pneumophila<\/em>: The Paradox of a Highly Sensitive Opportunistic Waterborne Pathogen Able to Persist in the Environment<strong>. <\/strong><strong>Front Microbiol.<\/strong>\u00a02016 Apr 8;7:486.<\/p>\n<p><strong>Schlusselhuber<\/strong><strong> M<\/strong>, Humblot V, Casale S, M\u00e9thivier C, Verdon J, Leippe M, Berjeaud JM. Potent antimicrobial peptides against <em>Legionella pneumophila<\/em> and its environmental host, <em>Acanthamoeba<\/em> <em>castellanii<\/em>. <strong>Applied Microbiology &amp; Biotechnology<\/strong>. 2015. DOI\u00a0: 10.1007\/s00253-015-6381-z.<\/p>\n<p>Loiseau C.*, <strong>Schlusselhuber M.*,<\/strong> Bigot R., Bertaux J., Berjeaud JM. Verdon J. Surfactin from <em>Bacillus<\/em> <em>subtilis<\/em> displays an unexpected anti-<em>Legionella<\/em> activity. <strong>Applied Microbiology &amp; Biotechnology.<\/strong> 2015. DOI\u00a0: 10.1007\/s00253-014-6317-z. <em>*co-premiers auteurs<\/em><\/p>\n<p><strong>Schlusselhuber M.<\/strong>, Guldbech, K., Sevin, C., Laugier, C., Leippe, M., Gr\u00f6tzinger, J., Leclercq R., Gigu\u00e8re, S., Cauchard J. Effectiveness of the antimicrobial peptide eCATH1 against antibiotic-resistant bacterial pathogens of horses<strong>. <\/strong><strong>FEMS Microbiology letter<\/strong>. 2014; 350(2):216-22.<\/p>\n<p><strong>Schlusselhuber M.<\/strong> \u00ab\u00a0Potentiel th\u00e9rapeutique de peptides antimicrobiens \u00e9quins\u00a0\u00bb, <strong>Presses acad\u00e9miques francophones<\/strong>. 2014. ISBN 978-3-8381-7126-5<\/p>\n<p><strong>Schlusselhuber M<\/strong>., Laugier C., Cauchard J. Potential of antimicrobial peptides as therapeutic tools against infectious diseases. <strong>Chapitre dans le livre <em>Antimicrobial Peptides: Properties, Functions and Role in Immune Response<\/em>, Nova Science publishers<\/strong>. 2013. ISBN : 978-1-62257-844-3<\/p>\n<p><strong>Schlusselhuber M. <\/strong>Les peptides antimicrobiens cationiques\u00a0: vers un renforcement de l\u2019arsenal th\u00e9rapeutique anti-infectieux\u00a0?. Journal des anti-infectieux. 2013. 15(3)\u00a0: 111\u2013118<\/p>\n<p><strong>Schlusselhuber<\/strong><strong> M<\/strong>, Torelli R, Martini C, Leippe M, Cattoir V, Leclercq R, Laugier C, Gr\u00f6tzinger J, Sanguinetti M, Cauchard J. The equine antimicrobial peptide eCATH1 is effective against the facultative intracellular pathogen <em>Rhodococcus equi<\/em> in mice. <strong>Antimicrobial Agents and Chemotherapy<\/strong>. 2013; 57(10):4615-21.<\/p>\n<p><strong>Schlusselhuber M<\/strong>., Jung S., Bruhn O., Goux D., Leippe M., Leclercq R., Laugier C., Gr\u00f6tzinger J., Cauchard J. <em>In vitro<\/em> potential of equine DEFA1 and eCATH1 as alternative antimicrobial drugs in rhodococcosis treatment. <strong>Antimicrobial Agents and Chemotherapy<\/strong>. 2012; 56(4):1749-55.<\/p>\n<p>Petry S., Tapprest J., Cauchard J., Philipot D., Bidaud P., <strong>Schlusselhuber M.,<\/strong> S\u00e9vin C., H\u00e9bert L., Cauchard S. &amp; Laugier C. (2012) Avanc\u00e9e des travaux pour une meilleure connaissance de la rhodococcose et l&rsquo;obtention de moyens de lutte plus efficaces. Equ\u2019id\u00e9e. N\u00b081 : 32-33<\/p>\n<p>Bruhn O., Cauchard J., <strong>Schlusselhuber M.,<\/strong> Gelhaus C., Podschun R., Thaller G., Laugier C., Leippe M., Gr\u00f6tzinger J. Antimicrobial properties of the equine alpha-defensin DEFA1 against bacterial horse pathogens. <strong>Veterinary Immunology &amp; Immunopathology.<\/strong> 2009;130:102-106.<\/p>\n<p>&nbsp;<\/p>\n<p><strong>Prix et distinctions : <\/strong><\/p>\n<ul>\n<li>Prix de la 2e meilleure communication orale (2014, International Symposium on AntiMicrobial Peptides)<\/li>\n<li>Prix du meilleur poster (2012, 40<sup>\u00e8mes<\/sup> Journ\u00e9es annuelles de l\u2019AVEF)<\/li>\n<\/ul>\n<p><strong>\u00a0<\/strong><strong>Contact\u00a0 : <\/strong>+33 (0) 2 31 56 57 82 \/\u00a0margot.schlusselhuber@unicaen.fr<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Ma\u00eetre de conf\u00e9rences, section 68 Doctorat d\u2019Universit\u00e9, Universit\u00e9 de Caen Basse Normandie (France)\/ Universit\u00e9 de Kiel (Allemagne), 2012 &nbsp; Int\u00e9r\u00eats de recherche :\u00a0Dans le cadre de l\u2019\u00e9tude des interactions entre microorganismes au sein de matrices alimentaires, mon activit\u00e9 porte essentiellement sur l\u2019\u00e9tude de mol\u00e9cules antimicrobiennes produites par diff\u00e9rentes bact\u00e9ries (peptides, lipopeptides, acides,&#8230;). Cette activit\u00e9 s\u2019articule &hellip; <a href=\"https:\/\/abte.eu\/index.php\/contact\/dr-margot-schlusselhuber\/\" class=\"more-link\">Continuer la lecture<span class=\"screen-reader-text\"> de &laquo;&nbsp;Dr Margot Schlusselhuber&nbsp;&raquo;<\/span><\/a><\/p>\n","protected":false},"author":2,"featured_media":0,"parent":33,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-645","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/abte.eu\/index.php\/wp-json\/wp\/v2\/pages\/645","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/abte.eu\/index.php\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/abte.eu\/index.php\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/abte.eu\/index.php\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/abte.eu\/index.php\/wp-json\/wp\/v2\/comments?post=645"}],"version-history":[{"count":4,"href":"https:\/\/abte.eu\/index.php\/wp-json\/wp\/v2\/pages\/645\/revisions"}],"predecessor-version":[{"id":663,"href":"https:\/\/abte.eu\/index.php\/wp-json\/wp\/v2\/pages\/645\/revisions\/663"}],"up":[{"embeddable":true,"href":"https:\/\/abte.eu\/index.php\/wp-json\/wp\/v2\/pages\/33"}],"wp:attachment":[{"href":"https:\/\/abte.eu\/index.php\/wp-json\/wp\/v2\/media?parent=645"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}